TKT — Transketolase
TKT belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TKT's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | mRNA Splicing RNA processing | CLTA, FKBP1A, HNRNPC, HNRNPK, RAC1, SLC25A3, SLC25A5, SRSF9 +1 more | View in SCUBA |
| Endothelial | Proteasomal Degradation Protein processing & ER | GNL3, HACD3, MRPL36, NME4, NUDT5, PON2, PSMA1, PSMB5 +3 more | View in SCUBA |
| Goblet cells | Mucosal Innate Defense Immune function | BOLA3, CTSS, DMBT1, ENO1, GPI, LGALS3BP, OLFM4, PIGR +4 more | View in SCUBA |
| Hematopoietic progenitor cells | Erythroid Glycolysis Erythropoietic | CMBL, ENO1, GAPDH, GYPC, LMO2, LY6E, MAP7, NENF +3 more | |
| Innate lymphoid cells | Proteasome & COPI Trafficking Protein processing & ER | CCT8, COPE, COPZ1, COX5A, FIBP, GPX4, LAMTOR4, MDH1 +5 more | View in SCUBA |
| Neutrophils | Pentose Phosphate Pathway Housekeeping | ANXA3, ARPC2, CAP1, CDA, GYG1, HMGB2, LBR, PGD +1 more |
About the gene
| Chromosome | 3: 53224712-53256052 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Transferase |
Function
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.