TNFAIP2 — TNF alpha induced protein 2
TNFAIP2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TNFAIP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Cytokine Inflammatory Response Inflammatory | CXCL2, DNAJB4, GFPT2, HES4, MAP3K8, MMP19, RASL11A, RGCC +4 more | View in SCUBA |
| Hematopoietic progenitor cells | Lymphoid-Primed Progenitor Lymphcyte development | ARHGAP27, CD22, COBLL1, LILRB2, LTB, PACSIN1, S100Z, SH3TC1 +4 more | |
| Lymphatic endothelial | NF-κB Inflammatory Activation Inflammation | ACHE, ANKLE2, CD200, CXCL1, CXCL8, HMGA1, ICOSLG, NFKB2 +9 more | View in SCUBA |
| Macrophages | NF-κB Activation Inflammatory | BCL3, BLOC1S6, CD83, CFLAR, CHMP1B, CNOT2, CSRNP1, CYLD +33 more | View in SCUBA |
| Pericytes | NF-κB Inflammatory Response Inflammatory | ABL2, ADAMTS9, ARL4A, BCL3, BHLHE40, FOSL2, ICAM1, KLF10 +3 more | View in SCUBA |
About the gene
| Synonyms | B94, EXOC3L3 |
|---|---|
| Chromosome | 14: 103121476-103137439 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters |
| Molecular function | Developmental protein |
| Biological process | Angiogenesis, Differentiation |
Function
May play a role as a mediator of inflammation and angiogenesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.