SCUBA

STK17A — Serine/threonine kinase 17a

STK17A belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

STK17A's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsTGF-beta response
Intercellular communication
CLU, COA1, ELK4, GLUL, GPR18, HDGFL3, ORAI2, RAB27B +3 moreView in SCUBA
EndothelialEndothelial Quiescence
Endothelial cell development
CCRL2, CDC42EP3, CGAS, CHSY1, CYTH1, HES5, HIPK3, ID1 +7 moreView in SCUBA
Gamma-delta T cellsImmature T Cell
T cell maturation
A1BG, ACP5, CD38, CD7, ID3, ITM2C, MZB1, NCF1 +7 more
Glial cellsInflammatory Cytokine Signaling
Inflammation
BACH1, BTG3, CSF1, FSTL3, NNMT, PAPPA, PDPN, RAB13 +3 moreView in SCUBA
Hematopoietic progenitor cellsRegulatory T-cell State
Lymphcyte development
CLEC2D, CYTIP, DDIT4, DOCK10, GSTA4, JCHAIN, MDFIC, MEF2A +9 more
Innate lymphoid cellsLymphocyte Apoptosis Regulation
Immune regulation
ANP32B, ARMCX3, CCDC69, CHD2, DHRS7, ELF1, FXYD5, GLIPR1 +14 moreView in SCUBA
MacrophagesNRF2 Oxidative Stress
Stress
ACOT9, AHRR, ARMC9, BASP1, CARD19, CCDC71L, CD226, CLDND1 +27 moreView in SCUBA
MonocytesIgA-Monocyte Activation
Innate immunity
AATK, AREG, ASPH, ATP2A3, CD82, FCAR, NIBAN2, SERPINB2 +3 moreView in SCUBA
Mucosal-associated invariant T cellApoptosis Regulation
Immune regulation
ARF4, ARRDC3, CARD8, CFLAR, CREBZF, MAPRE2, NABP1, PCF11 +1 more
Natural Killer cellsILC1/NK Cytotoxic
Cytotoxicity
A1BG, CASK, CLDND1, EIF3G, GZMK, ITM2C, KLRB1, NCF1 +4 moreView in SCUBA

About the gene

SynonymsDRAK1
Chromosome7: 43582758-43650713
Predicted locationMembrane
Essential geneNo
Protein classEnzymes, Plasma proteins, Predicted membrane proteins
Molecular functionKinase, Serine/threonine-protein kinase, Transferase
Biological processApoptosis

Function

Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.