PTMS — Parathymosin

PTMS belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PTMS's module in each cell type

Cell type	Module	Shares the module with
CD19⁺ B cells	Cytoskeleton/motility migration & adhesion	ANXA2, ANXA4, BHLHE41, C4orf48, CAPG, CAPN2, CIB1, ISCU +11 more	View in SCUBA
CD4⁺ T cells	T cell exhaustion Exhaustion	CD247, CD38, CD59, FLT1, GAN, IKBKB, LAG3, LRBA +3 more	View in SCUBA
Endothelial	Inflammatory Stress Response Inflammation	ADI1, APLN, ARL6IP1, ARL6IP4, CCDC88A, DAP, GPR68, HEBP2 +11 more	View in SCUBA
Hematopoietic progenitor cells	T-cell Progenitor Lymphcyte development	DSC2, GATA3, HOXB5, LAG3, MDK, OPTN, SELENOP, SKAP1 +2 more
Lymphatic endothelial	Mitochondrial OxPhos Complex Mitochondrial & OxPhos	COX6A1, COX6B1, COX6C, COX7A2, COX8A, DAD1, NDUFA1, NDUFB4 +6 more	View in SCUBA
Macrophages	Inflammasome Oxidative Stress Inflammatory	ABI3, ADISSP, AKR1A1, ARHGDIB, ARPC1B, ASCL2, BLVRA, C1orf54 +33 more	View in SCUBA
Monocytes	Monocyte Tissue Infiltration Migration & adhesion	CD59, CDCP1, FPR3, NRP1, NRP2, PDE4DIP, PLAU, PMP22 +3 more	View in SCUBA
Mucosal-associated invariant T cell	Metabolic Homeostasis Housekeeping	ADIPOR1, BIRC3, COQ10B, CREBRF, EIF1AX, GNAI3, H2AC20, KLF11 +10 more

About the gene

Synonyms	ParaT
Chromosome	12: 6765516-6770952
Predicted location	Intracellular
Essential gene	Yes
Protein class	Essential proteins, Predicted intracellular proteins
Biological process	Immunity

Function

Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.