SNRK — SNF related kinase
SNRK belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SNRK's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | GIMAP survival Immune regulation | ABLIM1, AKT3, ANKRD13D, ARL4C, C16orf54, CA5B, COPA, CRBN +16 more | View in SCUBA |
| Endothelial | Arterial EC Identity Endothelial cell development | ACVRL1, ANXA11, ATP13A2, ENG, HPCAL1, HYAL1, LDB2, MACF1 +7 more | View in SCUBA |
| Gamma-delta T cells | ER Protein Translocation Protein processing & ER | ATG2A, BEST1, CLSTN1, CTDSP2, GALC, GSE1, HAPSTR1, HOOK2 +12 more | |
| Lymphatic endothelial | Hypoxia Response Stress | CNTNAP3B, ENOSF1, FBN1, FKBP5, FOXP2, HIF3A, HMCN1, KAT2B +11 more | View in SCUBA |
| Mucosal-associated invariant T cell | NF-κB RNA Regulation RNA processing & translation | ARIH2, ATP1A1, BCLAF1, BNIP2, CALR, COG3, DDX6, EIF4G2 +14 more | |
| Pericytes | Pericyte Vascular Identity Developmental | AHR, ARHGAP29, CA4, CD46, MEF2C, MYO6, NOTCH1, PDE1C +10 more | View in SCUBA |
| Smooth muscle cells | Notch-TGFbeta Signaling Development | ACKR3, AFAP1L2, CSRNP3, GJC1, HTR1F, JAG1, LRRC10B, RAP2A +3 more | View in SCUBA |
About the gene
| Synonyms | FLJ20224, HSNFRK, KIAA0096 |
|---|---|
| Chromosome | 3: 43286512-43424764 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Kinase, Serine/threonine-protein kinase, Transferase |
Function
May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.