LAYN — Layilin
LAYN belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LAYN's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | LAYN+ tissue Treg Immune regulation | BEX3, CADM1, CHRNA6, EPHX2, FLVCR2, GNG8, IKZF4, LAPTM4B +7 more | View in SCUBA |
| CD8⁺ T cells | TCR Activation & Modulation Exhaustion | ADGRG1, AKAP5, CTLA4, ENTPD1, ETV1, GALNT2, MAST4, SOX4 | View in SCUBA |
| Endothelial | Venous EC Identity Endothelial cell development | CAVIN2, CEACAM1, CYBA, DNMBP, EFCC1, EPHX1, GMFG, HID1 +7 more | View in SCUBA |
| Gamma-delta T cells | IRF4 T-cell Activation T cell maturation | APOA1, APOA4, CD59, FCER1G, FES, FUCA1, GEM, GRAMD2B +14 more | |
| Innate lymphoid cells | ILC Survival Residency Gut residency | ARID4B, BAZ1A, BCL2A1, CD44, CSF2, CTSH, CXCL8, DUSP4 +25 more | View in SCUBA |
| Lymphatic endothelial | ECM Remodeling TGFb migration & adhesion | CCDC80, CCND1, CHRDL1, CRIP1, CTSH, ECSCR, HS3ST1, IARS2 +8 more | View in SCUBA |
| Mucosal-associated invariant T cell | Tc17 / MAIT17 Tc17 program | AHR, BAIAP2, CA10, CCR9, GFPT2, HIC1, IL17A, IL2 +5 more |
About the gene
| Synonyms | FLJ30977, FLJ31092 |
|---|---|
| Chromosome | 11: 111540280-111561745 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Receptor for hyaluronate
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.