PRDX2 — Peroxiredoxin 2
PRDX2 belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PRDX2's module in each cell type
About the gene
| Synonyms | MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA |
|---|---|
| Chromosome | 19: 12796820-12801800 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Cancer-related genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Antioxidant, Oxidoreductase, Peroxidase |
Function
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.