SCUBA

RER1 — Retention in endoplasmic reticulum sorting receptor 1

RER1 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

RER1's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsProteostasis OxPhos
Housekeeping
AIP, ARPC1B, ATP6V1F, C4orf48, CHMP2A, IL2RG, NDUFA13, NDUFB10 +6 moreView in SCUBA
CD8⁺ T cellsProteostasis Translation
Protein processing & ER
BZW1, CCT5, CCT7, EIF2S2, HNRNPC, HNRNPM, MDH1, PCBP1 +3 moreView in SCUBA
EndothelialER-Golgi Trafficking
Protein processing & ER
ARPC1A, CCT8, FIBP, GDI2, GGCT, LMAN2, MAP2K2, MRPS16 +10 moreView in SCUBA
FibroblastsER Protein Processing
Vesicular traficking
ARPC2, ENO1, GTF3C6, KDELR2, LMAN1, OSTC, P4HB, PRDX4 +5 moreView in SCUBA
Gamma-delta T cellsMitoribosome Small Subunit
Mitochondrial & OxPhos
ACADM, C14orf119, CHCHD1, COA3, COA4, COMMD8, GALK1, GEMIN6 +24 more
Innate lymphoid cellsRNA Chromatin Regulation
RNA processing & translation
ACADM, AURKAIP1, BUD23, CBX3, CMC2, COPB1, DNAJA2, DYNC1LI1 +19 moreView in SCUBA
MacrophagesER Protein Processing
Housekeeping
ACTR1A, ANXA7, ATP6AP1, ATP6AP2, ATP6V0B, ATP6V0E1, AUP1, BCAP31 +41 moreView in SCUBA
Mucosal-associated invariant T cellER & Mitochondrial Assembly
Protein processing & ER
ANAPC11, ARRDC1, ATP5MC1, COA3, CSTB, DECR1, GSTK1, HINT2 +9 more

About the gene

Chromosome1: 2391775-2405442
Predicted locationMembrane
Essential geneNo
Protein classPredicted membrane proteins, Transporters

Function

Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.