SCUBA

TRAPPC1 — Trafficking protein particle complex subunit 1

TRAPPC1 belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

TRAPPC1's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsActin Cytoskeleton
Cytoskeletal
ACTB, ACTG1, ACTR3, ARPC1B, ARPC2, ARPC4, ARPC5, BRK1 +14 moreView in SCUBA
CD4⁺ T cellsCytoskeleton & metabolism
Cytoskeletal
ATP5F1D, ATP5MC3, ATP6V0E1, BRK1, CAP1, LCK, MYL6, NEDD8 +11 moreView in SCUBA
CD8⁺ T cellsActin Cytoskeleton
Cytoskeletal
ACTB, ARF6, ARPC1B, ARPC4, BRK1, CAPZB, CFL1, CORO1A +10 moreView in SCUBA
EndothelialMitochondrial Oxidative Stress
Stress
AGTRAP, AP2M1, ECHS1, ECSCR, EDF1, EIF5A, NEDD8, PARK7 +5 moreView in SCUBA
Gamma-delta T cellsCytotoxic Effector Actin
cytotoxicity
ARPC2, ARPC5, ATOX1, BRK1, CFL1, CLIC1, CORO1A, DBI +14 more
Innate lymphoid cellsActin Cytoskeleton Dynamics
Cytoskeleton & motility
ACTB, ACTG1, ACTR3, ANAPC11, AP2S1, ARPC5, CALM3, CAPZB +11 moreView in SCUBA
MacrophagesOxidative Phosphorylation
Mitochondrial & OxPhos
ATP5F1C, ATP5MC3, ATP5PD, ATP5PO, COX5B, COX6C, LAMTOR2, MICOS10 +7 moreView in SCUBA
Mucosal-associated invariant T cellImmunoproteasome Activity
Inflammation
ABRACL, ARPC5, BANF1, CARD16, CISD3, CYBC1, GIMAP2, IMP3 +4 more
Natural Killer cellsEnergy Metabolism
Metabolism
ARL6IP4, ATP5MC2, BLOC1S1, NDUFA11, NDUFB9, PGAM1, PKMView in SCUBA

About the gene

SynonymsBET5, MUM2
Chromosome17: 7930345-7932123
Predicted locationIntracellular
Essential geneYes
Protein classEssential proteins, Predicted intracellular proteins
Biological processER-Golgi transport, Transport

Function

May play a role in vesicular transport from endoplasmic reticulum to Golgi

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.