SCUBA

ZNF331 — Zinc finger protein 331

ZNF331 belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ZNF331's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsHypoxia/metabolic stress
Stress
ALG13, ARL4A, C9orf72, HIP1R, PDE4B, SC5D, SLC2A3, TENT5C +2 moreView in SCUBA
CD4⁺ T cellsImmediate early activation
TCR/AP1/NFKb pathway
ALG13, AREG, BCAS2, C9orf72, CXCR4, FAM222A, HIP1R, NR4A2 +18 moreView in SCUBA
Gamma-delta T cellsChromatin Epigenetic Regulation
DNA/chromatin regulation
ADNP2, ARID4B, CEBPZ, ELL2, ENSG00000285976, ETF1, HIPK1, JMJD1C +17 more
Innate lymphoid cellsNR4A Activation Response
activation
ALG13, ARL4A, BCAS2, CASP3, CHMP1B, CREM, DDX24, DLL1 +16 moreView in SCUBA
MacrophagesNF-κB Activation
Inflammatory
BCL3, BLOC1S6, CD83, CFLAR, CHMP1B, CNOT2, CSRNP1, CYLD +33 moreView in SCUBA
MonocytesComplement Receptor Activation
Lysosomal & pahgocytosis
AVPI1, C5AR1, C5AR2, CLEC7A, CSF2RA, MAT2A, METRNL, PTPRE +1 moreView in SCUBA
Mucosal-associated invariant T cellNF-κB Activation
Inflammation
DUSP5, DUSP8, ELL2, GABARAPL1, IRF2BP2, MAFF, NAMPT, NFKB1 +8 more
Natural Killer cellsNK Activation Response
activation
CREM, EIF1, FTH1, MAFF, NR4A2, SELENOK, SRGNView in SCUBA
Smooth muscle cellsNR4A-ADAMTS Activation
Stress
ADAMTS1, ADAMTS4, ADAMTS9, AVPR1A, DUSP8, HIPK2, KLF9, MYC +5 moreView in SCUBA

About the gene

SynonymsRITA, ZNF361, ZNF463
Chromosome19: 53519527-53580269
Predicted locationIntracellular
Essential geneNo
Protein classCancer-related genes, Predicted intracellular proteins, Transcription factors
Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Function

May be involved in transcriptional regulation. May play a role in spermatogenesis

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.