SSR3 — Signal sequence receptor subunit 3
SSR3 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SSR3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Nucleocytoplasmic Transport RNA processing & translation | KHDRBS1, KPNB1, MAT2A, NFATC2IP, RBMX, SNX5, TRA2B | View in SCUBA |
| Endothelial | NF-κB Oxidative Stress Stress | ACP1, ALDH7A1, ARHGDIB, CCDC85C, CDC25B, CDKN3, CMSS1, COPRS +13 more | View in SCUBA |
| Fibroblasts | ER Protein Processing Vesicular traficking | ARPC2, ENO1, GTF3C6, KDELR2, LMAN1, OSTC, P4HB, PRDX4 +5 more | View in SCUBA |
| Goblet cells | Mucin Folding Machinery Mucus production & secretion | AGR2, KDELR2, MYDGF, OSTC, PPIB, SEC11C, SEC61B, SEC61G | View in SCUBA |
| Macrophages | Actin Cytoskeleton Organization Cytoskeletal | ACTR3, ARF1, ARHGDIA, ARPC4, CDC42, DERL1, EIF4G2, GARS1 +20 more | View in SCUBA |
| Pericytes | ER Protein Folding Stress | AP2S1, CALU, DYNLT1, IKBIP, KDELR2, MYDGF, OSTC, P4HB +1 more | View in SCUBA |
| Smooth muscle cells | ER Secretory Trafficking Protein processing & ER | ARF4, DEGS1, GYPC, P4HB, PDIA6, SH3PXD2A, TMED9, TMEM123 | View in SCUBA |
About the gene
| Synonyms | TRAPG |
|---|---|
| Chromosome | 3: 156539553-156555149 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
Function
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.