SCUBA

TMSB10 — Thymosin beta 10

TMSB10 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

TMSB10's module in each cell type

Cell typeModuleShares the module with
EnterocytesRedox Detoxification
Stress		CD9, CDX1, CYBA, GSTK1, GSTP1, KRT18, PYCARD, SEC61B +3 moreView in SCUBA
FibroblastsHomeostatic Fibroblast Identity
ECM production		ADGRL2, C1S, DCN, DKK3, DPYSL2, IL34, IL6ST, LUM +6 moreView in SCUBA
Gamma-delta T cellsEffector IFN Response
cytotoxicity		AGTRAP, ANXA1, B2M, CYBA, EMP3, FXYD5, GZMM, IFITM1 +9 more
Goblet cellsActin Dynamics
Cytoskeletal		ABRACL, CD24, CFL1, MYL12A, NDUFB4, NDUFS5, OCIAD2, PIN4 +3 moreView in SCUBA
Innate lymphoid cellsER-Golgi Trafficking
Protein processing & ER		ATP2B1, ATP6V1D, CAPZA2, CGGBP1, CNOT4, COPS5, CRIPT, CSTB +15 moreView in SCUBA
MacrophagesMHC-II Antigen Presentation
Innate immunity		AIF1, B2M, C1QA, C1QB, C1QC, CD68, CD74, CST3 +19 moreView in SCUBA
Mucosal-associated invariant T cellNADPH Oxidase & Innate Immune
Inflammation		ATP5F1D, ATP5MC3, COX5A, CYBA, FXYD5, GABARAP, GNG5, HIGD2A +9 more
Natural Killer cellsNK Cytotoxic Signaling
Cytotoxicity		APOBEC3G, B2M, CALM1, CD48, GLIPR2, HCST, MYL12A, TRGC1 +1 moreView in SCUBA

About the gene

SynonymsTB10
Chromosome2: 84905656-84906671
Predicted locationIntracellular
Essential geneYes
Protein classEssential proteins, Plasma proteins, Predicted intracellular proteins
Molecular functionActin-binding

Function

Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.