RASD1 — Ras related dexamethasone induced 1
RASD1 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RASD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Hypoxia-driven EMT Stress | ARC, CITED2, CSKMT, DDIT4, FAM43A, FAM53C, HBEGF, HEXIM1 +7 more | View in SCUBA |
| Gamma-delta T cells | AP-1 Immediate Early Response Stress | BRD2, CITED2, CSKMT, EGR1, EIF4A2, FRAT1, FRAT2, GADD45B +25 more | |
| Glial cells | Hypoxia mTOR Stress Stress | AMD1, CDKN2AIP, CITED2, DDIT4, HEXIM1, HSPA2, IFRD1, INTS6 +3 more | View in SCUBA |
| Hematopoietic progenitor cells | Regulatory T-cell State Lymphcyte development | CLEC2D, CYTIP, DDIT4, DOCK10, GSTA4, JCHAIN, MDFIC, MEF2A +9 more | |
| Innate lymphoid cells | ILC3 identity Differentiation | BHLHE40, BRD4, CASK, CITED2, GLUL, GNAS, HECA, IGFBP7 +19 more | View in SCUBA |
| Lymphatic endothelial | Lymphatic Valve Formation Valve formation | CCN1, CCN2, DUSP2, FOXC1, GADD45B, GADD45G, GATA2, HES5 +9 more | View in SCUBA |
| Smooth muscle cells | NR4A-ADAMTS Activation Stress | ADAMTS1, ADAMTS4, ADAMTS9, AVPR1A, DUSP8, HIPK2, KLF9, MYC +5 more | View in SCUBA |
About the gene
| Synonyms | AGS1, DEXRAS1 |
|---|---|
| Chromosome | 17: 17494437-17496395 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Human disease related genes, Predicted intracellular proteins |
Function
Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65 (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.