SCUBA

RAB11FIP1 — RAB11 family interacting protein 1

RAB11FIP1 belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

RAB11FIP1's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsChromatin Modification
DNA/chromatin regulation
AKAP13, CREBRF, EPC1, GCC2, GPBP1, JMJD1C, KMT2E, OFD1 +6 moreView in SCUBA
CD4⁺ T cellsMAF regulatory program
Immune regulation
AKAP13, ARID4B, DTHD1, FYN, IKZF3, ISCU, LIMA1, LIMS1 +12 moreView in SCUBA
Gamma-delta T cellsAHR/NF-κB Survival
Immune regulation
ABCC1, AHR, ANKRD37, AREG, BAIAP2, BCL2L11, BEND4, BIRC3 +24 more
Goblet cellsGoblet Cell Differentiation
Epithelial development
CLDN4, EIF1, ELF3, KLF3, KLF4, MIDN, PPP1R15A, TOB1View in SCUBA
Hematopoietic progenitor cellsLymphocyte Signaling
Lymphcyte development
ADGRG5, AHR, AKNA, CARD11, CORO1A, CYTH4, KIAA0930, LSP1 +3 more
Innate lymphoid cellsSplicing & Transcription
RNA processing & translation
ACTR2, BDP1, CDC5L, CYLD, DHX36, FXR1, GPATCH2, MTPN +12 moreView in SCUBA
Lymphatic endothelialLymphatic Specification
endothelial development
ARHGAP29, BOD1L1, CALD1, CLCN3, DECR1, GCC2, MINDY2, MPHOSPH8 +9 moreView in SCUBA
MacrophagesAutophagy Vesicle Trafficking
Lysosomal & pahgocytosis
ADNP2, AGO2, AP1G1, ARFGAP3, ATG2A, BANP, CHD1, CHD2 +26 moreView in SCUBA
Monocytesp38 MAPK Signaling
Inflammatory
CREB5, CRISPLD2, FBXL5, LBR, LRRK2, MAPK14, MEGF9, NFE2 +5 moreView in SCUBA

About the gene

SynonymsFLJ22524, FLJ22622, Rab11-FIP1, RCP
Chromosome8: 37858618-37899497
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Biological processProtein transport, Transport

Function

A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis. Interaction with RAB14 may function in the process of neurite formation.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.