PTGER4 — Prostaglandin E receptor 4
PTGER4 belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PTGER4's module in each cell type
About the gene
| Synonyms | EP4 |
|---|---|
| Chromosome | 5: 40679915-40693735 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
Function
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.